Spring is coming, is your nose itching? Kimishige Ishizaka and Teruko Ishizaka together extensively contributed to the research of allergy. Together, they discovered the immunoglobulin E (IgE) antibodies, crucial in allergic reactions.

Additionally, they elucidated the mechanisms of allergy, including those triggering histamine release, explaining the allergy symptoms.

Their discovery enabled a better understanding of allergic diseases, and therefore, the basis for better prevention and treatment.